Gastroesophageal Reflux Disease – Pharmacology for Nurses

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Chapter 50: Acid-Controlling Test, Gastroesophageal Reflux Disease, Pharmacology for Nurses

The key terms in this Pharmacology course include Acid-controlling, Gastroesophageal Reflux Disease ( GERD ), Proton Pump Inhibitors, Nurse, Cytoprotective Drug, Sucralfate, Fluconazole, Pharmacology for Nurses: Practical Applications


Which drug class would be used as a first-line therapy for gastroesophageal reflux disease ( GERD ) that has not responded to customary medical treatment?

a. Proton pump inhibitors

b. Mucosal protectants

c. Antacids

d. H2 blockers


What is the generic name for a cytoprotective drug ?

a. Sucralfate

b. Omeprazole

c. Famotidine

d. Esomeprazole


Proton pump inhibitors reduce but do not completely eliminate acid secretion.

True

False


Nizatidine binds enzymes of the hepatic cytochrome P-450 and therefore may raise blood concentrations of certain drugs. 

True

False


The normal PH of stomach acid is which of the following ? 

a. 2-4

b. 3-7

c. 1-4

d. 1-3


What conditions are considered contradictions for use of antifungal medications(Select all that apply.)

Kidney failure

Respiratory failure

Liver failure

Heart failure

Pancreatic failure

Drug allergy, liver failure, kidney failure, and porphyria (for griseofulvin) are the most common contraindications for antifungal drugs.


Which antifungal drug can be given intravenously to treat severe yeast infections as well can be prescribed as a one-time oral dose to treat vaginal yeast infections?

Fluconazole

Nystatin

Caspofungin

Voriconazole

Fluconazole is an antifungal drug that does not cause the major adverse effects of amphotericin when given intravenously. It is also very effective against vaginal yeast infections, and a single dose is often sufficient to treat vaginal infections.


Which drug class would be used as a first-line therapy for gastroesophageal reflux disease ( GERD )

that has not responded to customary medical treatment?

a. Proton pump inhibitors

b. Mucosal protectants

c. Antacids

d. H2 blockers


Which antifungal drug can be given intravenously to treat severe yeast infections as well can be prescribed as a one-time oral dose to treat vaginal yeast infections?

Fluconazole

Nystatin

Caspofungin

Voriconazole

Fluconazole is an antifungal drug that does not cause the major adverse effects of amphotericin when given intravenously. It is also very effective against vaginal yeast infections, and a single dose is often sufficient to treat vaginal infections.