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Chapter 37: Respiratory Drug Test, Aminophylline, Pharmacology for Nurses: Practical Applications

The key terms in this Pharmacology course include Chapter, Respiratory Drug Test, Chronic Obstructive Pulmonary Disease, Aminophylline, Therapeutic Response, Pharmacology for Nurses: Practical Applications


A patient is taking intravenous aminophylline for a severe exacerbation of chronic obstructive pulmonary disease. The nurse will assess for which therapeutic response?

Increased heart rate

Increased respiratory rate

Increased ease of breathing

Increased sputum production

The therapeutic effects of bronchodilating drugs such as xanthine derivatives include increased ease of breathing. The other responses are incorrect.


The nurse is providing instructions about the Advair inhaler (fluticasone propionate and salmeterol). Which statement about this inhaler is accurate?

Patients need to avoid drinking water for 1 hour after taking this drug.

It is used for the prevention of bronchospasms.

It needs to be used with a spacer for best results.

It is indicated for the treatment of acute bronchospasms.

Salmeterol is a long-acting beta2 agonist bronchodilator, while fluticasone is a corticosteroid. In combination, they are used for the maintenance treatment of asthma and COPD. As a long-acting inhaler, Advair is not appropriate for treatment of acute bronchospasms. The other statements are incorrect.


A patient has prescriptions for two inhalers. One inhaler is a bronchodilator, and the other is a corticosteroid. Which instruction regarding these inhalers will the nurse give to the patient?

“It does not matter which inhaler you use first.”

“Take the corticosteroid inhaler first.”

“Take these two drugs at least 2 hours apart.”

“Take the bronchodilator inhaler first.”

An inhaled bronchodilator is used before the inhaled corticosteroid to provide bronchial relaxation/dilation before administration of the anti-inflammatory drug.


What are the most common adverse effects of montelukast and zafirlukast ?

a. headache

b. nausea

c. dizziness

d. constipation

dizziness

headache nausea

constipation


Drugs like Rifampin and phenobarbital are enzyme inducers which can increase drug concentrations of Montekulast. True or False?

True

False


During a teaching session for a patient who will be receiving a new prescription for the LTRA montelukast ( Singulair ) , the nurse will tell the patient that the drug has which therapeutic effect

a. Improves the respiratory drive

b. Loosens and removes thickened secretions

c. Reduces inflammation in the airway

d. Stimulates immediate bronchodilation

Loosens and removes thickened secretions

Stimulates immediate bronchodilation

Improves the respiratory drive

Reduces inflammation in the airway


The nurse is preparing to administer the elixir form of theophylline to a patient with a Peg tube. The dose is 240 mg daily and the medication is available in a concentration of 80 mg / 15 ml. How many milliliters will the nurse give per dose?

Follow your answer with ml for full credit. 

46 ml

45 ml

42 ml

40 ml