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Osteoclasts Development – Biology Test

The key terms of Biology Test include, Bone, Cartilage, Growth, Osteoclasts, Development, Epiphysis, Osteoblasts, Communicate, Increase, Osteocytes.


Bone growth in which the bone increases in diameter is called:

interstitial growth.
epiphyseal growth.
appositional growth. – correct
endosteal growth.
cancellous bone growth.


Which is not true about bone remodeling?

Occurs throughout life.
Assists in the maintenance of calcium and phosphate levels in the body.
Occurs at both the endosteal and periosteal surfaces of the bone.
It occurs only at articular surfaces. – correct
It can occur in response to stress on a bone.


The type of bone tissue that is replaced more frequently is ________ bone; the part of the femur that is replaced more frequently is the __________.

compact, distal epiphysis
compact, diaphysis
spongy, distal epiphysis – correct
spongy, diaphysis


Mechanical stress of bones, such as that caused by weight lifting, is detected by:

osteocytes, which then communicate to osteoblasts to increase synthesis of osteoid. – correct
osteoclasts, which then communicate to osteocytes to increase the size of lacunae.
chondrocytes, which then trigger osteoblasts to increase bone in a lengthwise fashion.
osteoblasts, which then communicate to osteocytes and osteoclasts to deposit more hydroxyapatite.


Endochondral ossification begins with a(n) _________ model.

mesenchyme
dense connective tissue
hyaline cartilage – correct
membranous
osteoid


When during human development does the process of ossification begin?

12 weeks after birth
12th-13th week of embryonic development – correct
8th-9th month of fetal development
3-4 months of age
10-25 years of age


The steps in the process of endochondral ossification are
a: Ossification center forms in the diaphysis.
b: Cartilage calcifies and a bone collar forms.
c: Ossification centers form in the epiphyses.
d: Bone replaces cartilage.
e: Epiphyseal plates ossify.
f: Cartilage model develops.
The correct chronological order for these steps is:

f. – b. – c. – d. – a. – e.
b. – c. – f. – a. – e. – d.
a. – c. – b. – d. – e. – f.
f. – b. – a. – c. – d. – e. – correct
a. – e. – c. – d. – b. – f.


During the process of endochondral ossification, chondrocytes in the cartilage model die. Why does this occur?

Blood supply to the cartilage is cut off by the developing periosteum.
Canaliculi connecting adjacent chondrocyte lacunae fuse.
Nutrients cannot diffuse to the chondrocytes through the calcified matrix. – correct
The developing bone collar secretes enzymes that destroy the chondrocytes.
Phagocytic osteoclasts in the new bone engulf and destroy the chondrocytes.


The zones found in an epiphyseal plate are
a: Calcified cartilage
b: Hypertrophic cartilage
c: Ossification
d: Resting cartilage
e: Proliferating cartilage
The correct order for these zones, beginning with the edge closest to the epiphysis and proceeding toward the diaphysis, is:

c – a – b – e – d
d – b – e – a – c
e – d – a – c – b
c – d – e – a – b
d – e – b – a – c – correct


Within which zone of the epiphyseal plate do cartilage cells undergo mitosis?

The zone closest to the medullary cavity
The zone closest to the epiphysis
The second closest bone to the medullary cavity
The second closest zone to the epiphysis – correct


Which is an accurate description of appositional bone growth?

Osteoblasts build bone at the circumferential lamellae while osteoclasts widen the medullary cavity. – correct
Osteoclasts build bone at the concentric lamellae while osteoblasts build bone at the interstitial lamellae.
Osteoblasts build bone at the concentric lamellae while osteoclasts build bone at the epiphyses.
Osteocytes build bone at the interstitial lamellae while osteoclasts expand the length of the medullary cavity.
Osteocytes and osteoclasts expand the bone at its epiphyses, chondrocytes construct cartilage.


Bone growth in which the bone increases in diameter is called:

interstitial growth.
epiphyseal growth.
appositional growth. – correct
endosteal growth.
cancellous bone growth.


Osteoclasts Development – Biology Test


Which is not true about bone remodeling?

Occurs throughout life.
Assists in the maintenance of calcium and phosphate levels in the body.
Occurs at both the endosteal and periosteal surfaces of the bone.
It occurs only at articular surfaces. – correct
It can occur in response to stress on a bone.


The type of bone tissue that is replaced more frequently is ________ bone; the part of the femur that is replaced more frequently is the __________.

compact, distal epiphysis
compact, diaphysis
spongy, distal epiphysis – correct
spongy, diaphysis


Mechanical stress of bones, such as that caused by weight lifting, is detected by:

osteocytes, which then communicate to osteoblasts to increase synthesis of osteoid. – correct
osteoclasts, which then communicate to osteocytes to increase the size of lacunae.
chondrocytes, which then trigger osteoblasts to increase bone in a lengthwise fashion.
osteoblasts, which then communicate to osteocytes and osteoclasts to deposit more hydroxyapatite.